Immunology has 10 ratings and 0 reviews: Published October 1st by W.H. Freeman & Company, Hardcover. Title, Immunology. Author, Janis Kuby. Edition, 3, illustrated, reprint. Publisher, W.H. Freeman, ISBN, , Length, pages. Originally authored by the award winning author Janis Kuby, "Immunology" remains the best selling textbook for the undergraduate course. The first and only.


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It is able to generate an enormous variety of cells and molecules capable of specifically recognizing and eliminat- ing an apparently limitless variety of foreign invaders.


These cells and molecules act together in a dynamic network whose complexity rivals that of the nervous system. Functionally, an immune response can be divided into two immunology by janis kuby activities—recognition and response. Immune recognition is remarkable for its specificity.

Kuby Immunology

The immune system is able immunology by janis kuby recognize subtle chemical differences that distinguish one foreign pathogen from another. Once a for- eign organism has been recognized, the immune system recruits a variety of cells and molecules to mount an appro- priate response, called an effector response, to eliminate or neutralize the organism.

In this way the system is able immunology by janis kuby convert the initial recognition event into a variety of effector responses, each uniquely suited for eliminating a particular type of pathogen. Later exposure to the same foreign organ- ism induces a memory response, characterized by a more rapid and heightened immune reaction that serves to elimi- nate the pathogen and prevent disease.

[Janis Kuby] Immunology

This chapter introduces the study of immunology from an historical perspective and presents a broad overview of the cells and molecules that compose the immune system, along with the mechanisms they use to protect the body against foreign invaders. Evidence for the presence of very simple immune systems in certain invertebrate organisms then gives an evolutionary perspective on the mammalian immune system, which is the major subject of this book.

El- ements of the primitive immune system persist in verte- brates as innate immunity along immunology by janis kuby a more highly evolved system of specific responses termed adaptive immunity. These two systems work in concert to provide a high degree of protection for vertebrate species.

Finally, in some circum- stances, the immune system fails to act as protector because of some deficiency in its components; at other times, it be- comes an aggressor and turns its awesome powers against its own host.

Kuby Immunology

In this introductory chapter, our description of immunity is simplified to reveal the essential structures and function of the immune system. Substantive immunology by janis kuby, ex- perimental approaches, and in-depth definitions are left to the chapters that follow.

These sections investigate the causes, consequences, or treat- ments of diseases rooted in impaired or hyperactive immune function. Historical Perspective The discipline of immunology grew out of the observation that individuals who had recovered from certain infectious diseases were thereafter protected from the disease.

Kuby immunology /Richard A. Goldsby, Thomas J. Kindt, Barbara A. Osborne. – National Library

Perhaps the earliest written reference to the phenomenon of immunity can be traced back to Thucydides, the great his- immunology by janis kuby of the Peloponnesian War. In describing a plague in Athens, he wrote in BC that only those who had recov- ered from the plague could nurse the sick because they would not contract the disease a second time.

The first recorded attempts to induce immunity deliber- ately were performed by the Chinese and Turks in the fif- teenth century.

Various reports suggest immunology by janis kuby the dried crusts derived from smallpox pustules were either inhaled into the nostrils or inserted into small cuts in the skin a technique called variolation. InLady Mary Wortley Montagu, the wife of the British ambassador to Constantinople, observed the positive immunology by janis kuby of variolation on the native population and had the technique performed on her own children.

The method was significantly improved by the English physician Edward Jenner, in Intrigued by the fact that milkmaids who had contracted the mild disease cowpox were subse- quently immune to smallpox, which is a disfiguring and of- ten fatal disease, Jenner reasoned that introducing fluid from a cowpox pustule into people i.

To test this idea, he inoculated an eight-year-old boy with fluid from a cowpox pustule and later intentionally infected the child with smallpox.

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